Analysis of TSH screening results of 42,979 newborns in Zhejiang Province.
- Author:
Yi-ping QU
1
;
Xi-lin YU
;
Min ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Congenital Hypothyroidism; Female; Humans; Hypothyroidism; epidemiology; Infant, Newborn; Male; Neonatal Screening; Sex Factors; Thyrotropin; blood
- From: Journal of Zhejiang University. Medical sciences 2003;32(4):345-348
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEDocument the prevalence of congenital hypothyroidism in Zhejiang Province, by neonatal screening of TSH.
METHODSDELFIA neonatal TSH kit was applied for the quantitative determination of thyrotropin in blood specimens dried on filter paper.
RESULTAmong the 42 979 newborns, 112 had elevated hTSH concentration in blood. All had T3, T4 and TSH concentrations measured in serum and 29 were diagnosed as congenital hypothyroidism. The diagnosis time was 13 to 59 days and mean time was (27.9+/-9.2) days.
CONCLUSIONThe incidence of congenital hypothyroidism in Zhejiang Province is not low. The TSH screening in newborns is significant in eugenics and the improvement of population quality.
