Clinical and histological features in 11 cases of castlemen
- Author:
Hung Phi Nguyen
- Publication Type:Journal Article
- Keywords:
Castlemen
- MeSH:
Lymphoproliferative Disorders;
diagnosis
- From:Journal of Vietnamese Medicine
2002;227(10):56-60
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Castlemen disease is a lymphoproliferative disorder of unknown etiology, was first described as a distinct entity by Castlemen et al in 1956. The disease has two clinical (localized and multicentric) and two histopathological forms (hyalinevascular and plasma cell). This disease is usually, clinically misunderstood as lymphoma, carcinoma metastatic-lymph nodes, or tuberculosis. We, therefore, represent clinicopathological findings of 11 cases of Castlemen disease seen in Hanoi K Hospital. Results: Most patients are women (F:M=4.5:1), age ranges from 15-52 year old with average is 33. The affected nodes are often enlarged (3cm in 63.6%). Localized form is prominent with proportion of 63.6%. The treatment is still problematic, but complete surgical excision is the treatment of choice for localized form and is generally curative.
