Glass transition of Chinese medicine extract powder and its application.
10.19540/j.cnki.cjcmm.20161222.043
- Author:
Xiao-Jian LUO
1
;
Hui LIU
1
;
Hong-Bo LIANG
2
;
Lei XIONG
2
;
Xiao-Yong RAO
1
;
Yin XIE
3
;
Yan HE
1
Author Information
1. Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
2. Nanchang Hangkong University, Nanchang 330063, China.
3. Jiangxi Institute For Drug Control, Nanchang 330029, China.
- Publication Type:Journal Article
- Keywords:
Chinese medicine extract powder;
caking;
glass transition;
glass transition temperature;
sticky wall;
sticky wheel
- From:
China Journal of Chinese Materia Medica
2017;42(1):192-197
- CountryChina
- Language:Chinese
-
Abstract:
Glass transition theory is an important theory in polymer science, which is used to characterize the physical properties. It refers to the transition of amorphous polymer from the glassy state to the rubber state due to heating or the transition from rubber state to glassy state due to cooling. In this paper, the glassy state and glass transition of food and the similar relationship between the composition of Chinese medicine extract powder and food ingredients were described; the determination method for glass transition temperature (Tg) of Chinese medicine extract powder was established and its main influencing factors were analyzed. Meanwhile, the problems in drying process, granulation process and Chinese medicine extract powder and solid preparation storage were analyzed and investigated based on Tg, and then the control strategy was put forward to provide guidance for the research and production of Chinese medicine solid preparation.
