Advances in animal model and traditional Chinese medicine prevention in coronary microvascular dysfunction.
10.19540/j.cnki.cjcmm.20161222.041
- Author:
Lei LI
1
;
Jian-Xun LIU
1
;
Jian-Xun REN
1
;
Hao GUO
1
;
Cheng-Ren LIN
1
Author Information
1. Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
- Publication Type:Journal Article
- Keywords:
animal model;
cardiac X-syndrome;
coronary microvascular dysfunction;
microvascular angina;
no-reflow after PCI;
traditional Chinese medicine
- From:
China Journal of Chinese Materia Medica
2017;42(2):254-258
- CountryChina
- Language:Chinese
-
Abstract:
Coronary microvascular dysfunction (CMD) is a common mechanism for some heart disease like cardiac X syndrome and no-reflow phenomenon after percutaneous coronary intervention(PCI). With the development of medical imageology, CMD has received increased attention. Animal model of CMD is indispensable tool for the research of pathogenesis and treatment evaluation, therefor choose an appropriate animal model is the first issue to carry out CMD research. Experimental and clinical studies have shown unique effectiveness of traditional Chinese medicine(TCM) in CMD therapy. Clarifying of the TCM therapeutic effect mechanisms and seeking an optimal solution of combination of traditional Chinese and western medicine will be the focus of future research. This paper reviewed the establishment and evaluation of CMD animal model, as well as the intervention study of TCM on CMD. The article aims to provide reference for the basic research of CMD and the TCM experimental study on CMD.
