Study on LDL adsorbent modified by lauric acid.
- Author:
Haixia CONG
1
;
Longbing DU
;
Bo FANG
;
Chao YOU
Author Information
1. Chemical Engineering Research Center, ECUST, Shanghai 200237, China.
- Publication Type:Journal Article
- MeSH:
Adsorption;
Blood Component Removal;
methods;
Chitosan;
chemistry;
Cholesterol, LDL;
blood;
isolation & purification;
Lauric Acids;
chemistry
- From:
Journal of Biomedical Engineering
2010;27(3):671-674
- CountryChina
- Language:Chinese
-
Abstract:
A hydrophobic low-density lipoprotein cholesterol (LDL-C) adsorbent was synthesized with lauric acid and chitosan. The condition for adsorption was obtained by investigating the influence of adsorbent amount and adsorption time. The results of adsorption in vitro showed that the average adsorption rates for total cholesterol (TC), LDL-C, high-density lipoprotein cholesterol (HDL-C) and total protein (TP) were 47.7%, 84.7%, 18.1% and 5.9% respectively. The adsorbent possesses good selectivity in removing LDL-C.
