Neutrophils in Immunity.
10.4167/jbv.2012.42.2.172
- Author:
So Youn WOO
1
Author Information
1. Department of Microbiology, School of Medicine, Ewha Womans University, Seoul, Korea. soyounwoo@ewha.ac.kr
- Publication Type:Letter
- Keywords:
Inflammation;
Antimicrobial;
Granule;
Neutrophil extracellular trap (NET)
- MeSH:
Autoimmunity;
Cytokines;
Inflammation;
Leukocytes;
Neutrophils;
Phagocytes;
Proteins
- From:Journal of Bacteriology and Virology
2012;42(2):172-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins, and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.