Adult Neurogenesis in the Central and Peripheral Nervous Systems.
- Author:
Hyun Jung KIM
1
;
Woong SUN
Author Information
1. Department of Anatomy, Korea University College of Medicine, Seoul, Korea. woongsun@korea.ac.kr
- Publication Type:Review
- Keywords:
Adult stem cells;
Neural stem cells;
Neurogenesis;
Central nervous system;
Peripheral nervous system
- MeSH:
Adult;
Adult Stem Cells;
Brain;
Central Nervous System;
Dentate Gyrus;
Embryonic Development;
Female;
Hippocampus;
Humans;
Neural Stem Cells;
Neurogenesis;
Peripheral Nervous System;
Pregnancy
- From:International Neurourology Journal
2012;16(2):57-61
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural stem cells (NSCs) are widely distributed in the central and peripheral nervous systems. Besides their ability to integrate into existing neural networks during physiological conditions, NSCs also proliferate and differentiate in response to injury, thus promising the potential use of endogenous NSCs for the treatment of neuropathological conditions. In this review, we discuss recent progress in the understanding of adult neurogenesis in the brain and peripheral nervous system.
