Systematic review of randomized controlled trials of acupuncture for glaucoma.
- Author:
Rui GAO
1
;
Chun-Hu SHI
;
Jin-Hui TIAN
;
Zhen KANG
Author Information
- Publication Type:Journal Article
- MeSH: Acupuncture Therapy; Glaucoma; drug therapy; therapy; Humans; Ophthalmic Solutions; therapeutic use; Randomized Controlled Trials as Topic; Treatment Outcome
- From: Chinese Acupuncture & Moxibustion 2011;31(12):1142-1145
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the efficacy of acupuncture for glaucoma.
METHODSThe search was conducted through database to identify randomized controlled trials of acupuncture for glaucoma until September 2010. The quality assessment, data extraction and Meta-analysis were performed by Cochrane Handbook for Systematic Re views of Interventions.
RESULTSEight articles were included. Meta-analysis showed that acupuncture did not decrease intraocular pressure compared with eye drops [SMD = -0.1 66, 95% CI (-1.45, 0.13)]. However, acupuncture increased the effectiveness rate of treatment for glaucoma [OR = 4.45, 95% CI (1.96,10.09)]. Compared with placebo, acupuncture did not decrease intraocular pressure 20 min after acupuncture (P = 0.13) and 24 hours after acupuncture (P = 0.21). Nonetheless, acupuncture increased the effectiveness rate of treatment for glaucoma [OR = 45.00, 95% CI (9.73, 208.08)]. Compared with acupuncture, quantitative acupuncture manipulation increased the effectiveness rates of treatment for glaucoma [OR = 2.23, 95% CI (1.14, 4.36)].
CONCLUSIONAcupuncture therapy has potential to increase effectiveness rates of treatment for glaucoma. It lacks reliable evidence to prove that acupuncture decreases intraocular pressure. More trials with high quality are needed to estimate adverse effects and cost effectiveness of acupuncture therapy.