Evaluation of the post-effect of acupuncture at Sanyinjiao (SP 6) under sleep deprivation by resting-state amplitude of low-frequency fluctuation: a fMRI study.
- Author:
Xi-Jian DAI
1
;
You-Jiang MIN
;
Hong-Han GONG
;
Lei GAO
;
Si-Yong WANG
;
Fu-Qing ZHOU
;
Xiang-Zuo XIAO
;
Bi-Xia LIU
Author Information
- Publication Type:Journal Article
- MeSH: Acupuncture Points; Acupuncture Therapy; Brain; diagnostic imaging; physiopathology; Female; Humans; Magnetic Resonance Imaging; Male; Radiography; Sleep Deprivation; diagnostic imaging; physiopathology; therapy; Young Adult
- From: Chinese Acupuncture & Moxibustion 2012;32(1):47-52
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo discuss the central modulating mechanism of Sanyinjiao (SP 6) and the amplitude of low-frequency fluctuation (ALFF) differences of the functional brain regions between SP 6 and sham acupoint.
METHODSSixteen volunteers accepted right Sanyinjiao (SP 6) (SP 6 group) or right sham (sham group) acupuncture for two times after 24 h sleep deprivation (SD), there was two weeks between two acupunctures. The needle was retained for 4 minutes and the brain fMRI scanning was performed by 3.0 TMR every time. The ALFF consequent data was processed by REST. One-sample t-test and two-pair t-test were performed by SPM5.
RESULTSSP 6 group mainly caused ALFF change in inferior parietal lobule, posterior cingulated while sham group in precuneus, posterior cingulated. SP 6 group increased ALFF in left fusiform temporal gyrus, medial frontal gyrus with no decreased regions compared with sham group.
CONCLUSIONSRetaining needle dose influence the activity of the brain region during resting-state in both group, especially the mood-related regions. And its mechanism is probably that the relevant effect is carried out by regulating function to target organs of complex brain network comprised of relevant functional center and related brain region. There are differences between SP 6 and Sham acupoint.
