Risk Factors for Subsequent Bladder Tumor in Upper Tract Urothelial Tumor.
- Author:
Gun Pyung KIM
1
;
Hyun Hag KIM
;
Bong Ryoul OH
;
Hyung Jin KIM
;
Soo Bang RYU
;
Young Kyung PARK
;
Yang Il PARK
Author Information
1. Department of Urology, Chonnam National University Medical School, Kwangju, Korea. sbryu@chonnam.ac.kr
- Publication Type:Original Article
- Keywords:
Urothelial tumor;
Urinary bladder;
Tumor recurrence;
Risk factor
- MeSH:
Chemotherapy, Adjuvant;
Follow-Up Studies;
Humans;
Incidence;
Lymph Nodes;
Neoplasm Metastasis;
Recurrence;
Retrospective Studies;
Risk Factors*;
Survival Rate;
Urinary Bladder Neoplasms*;
Urinary Bladder*
- From:Korean Journal of Urology
2001;42(12):1258-1264
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine the clinical and pathological risk factors for subsequent bladder tumor in patients with primary upper tract urothelial tumor, we retrospectively analyzed patients with upper tract urothelial tumor, focusing on the clinicopathological features of subsequent bladder tumor. MATERIALS AND METHODS: Risk factors, disease free rate and survival were assessed with clinicopathological features in 56 patients with upper tract urothelial tumor operated between 1989 and 1998. We excluded the patients with lymph node metastasis or distant metastasis, those with a short period of follow-up, and those having a previous history of bladder tumor. Risk factors such as sex, age, location of tumor, size of tumor, number of tumor, synchronous bladder tumor, preoperative urine cytology, stage, grade, operation method, and adjuvant chemotherapy were investigated. RESULTS: Initial subsequent bladder tumor was found in 36 patients (53.6%) during follow-up period of 44 months (range 13 to 111). Among several clinicopathological factors examined, only urine cytology was significantly correlated with the incidence of subsequent bladder tumor (p<0.05). Sex, age, location of tumor, size of tumor, number of tumor, synchronous bladder tumor, stage, grade, operation method, or adjuvant chemotherapy did not affect subsequent bladder tumor recurrence. There was no significant difference in survival rates between the patients with and without subsequent bladder tumor. CONCLUSIONS: Of the clinical and pathological risk factors for subsequent bladder tumor in patients with primary upper tract urothelial tumor, only preoperative urine cytology was significantly correlated with subsequent bladder tumor.
