Clinical study on effects of tiepi fengdou granule/capsule combined with chemotherapy and/or radiotherapy in treating lung cancer with Qi-Yin asthenia syndrome.
- Author:
Xiao-ping CHEN
1
;
Yi-ping ZHANG
;
Xian-ru ZHU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Antineoplastic Combined Chemotherapy Protocols; therapeutic use; Combined Modality Therapy; Diagnosis, Differential; Drugs, Chinese Herbal; administration & dosage; Female; Humans; Karnofsky Performance Status; Lung Neoplasms; drug therapy; radiotherapy; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Qi; Yin Deficiency; drug therapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26(5):394-397
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the clinical efficaly and safety of Tiepi Fengdou Granule (TFG) and Capsule (TFC) combined with chemotherapy and/or radiotherapy in treating lung cancer patients with Qi-Yin asthenia syndrome (QYAS).
METHODSEighty patients were randomly assigned into 3 groups: the TFG group (32 cases), the TFC group (32 cases) and the Shengmai Capsule control group (16 cases). Changes of symptoms of QYAS, main symptoms of lung cancer, Karnofsky scoring as well as the blood routine test were observed.
RESULTSThe total effective rate of symptom improving in the TFG group and the TFC group was 81.2% and 93.3% respectively, showing insignificant difference between the 2 groups (P > 0.05), but both were higher than that in the Shengmai Capsule control group (50.0%, P < 0.05 and P < 0.01). Additionally, as compared with those before treatment, the neutrophil count increased and the lymphocytes count obviously decreased in the TFC group after treatment (all P < 0.05).
CONCLUSIONBoth dose-forms of the remedies, TFC and TFG, have significant effects in treating lung cancer with QYAS, but with insignificant difference between them.
