Effect of yuquan pill on proinflammatory cytokines in patients with type 2 diabetes mellitus.
- Author:
Yin-quan DENG
1
;
Xiao-fen FAN
;
Guo-lin WU
Author Information
- Publication Type:Journal Article
- MeSH: Acarbose; therapeutic use; Adult; Aged; C-Reactive Protein; metabolism; Diabetes Mellitus, Type 2; blood; drug therapy; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Hypoglycemic Agents; therapeutic use; Interleukin-6; blood; Male; Middle Aged; Phytotherapy; Tumor Necrosis Factor-alpha; blood
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26(8):706-709
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Yuquan Pill (YP) on proinflammatory cytokines in patients with type 2 diabetes mellitus (DM2).
METHODSNinety patients with DM2 were randomly divided into the treated group and the control group by the ratio of 2:1. Both groups were treated with Glucobay on the base of dietary and exercise therapy for 3 months, with YP, given to the treated group additionally 6 g four times a day. And the changes of proinflammatory cytokines, including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), etc. were observed.
RESULTSThe levels of serum CRP,TNF-alpha and IL-6 significantly lowered after treatment in both groups (P<0.01), and the improvement in the treated group was superior to that in the control group (P<0.01).
CONCLUSIONYP could reduce the levels of the increased proinflammatory cytokines in patients with DM2.
