Effect of combination of Chinese and Western medicines on sinus rhythm maintenance in patients with auricular fibrillation after conversion.
- Author:
Pei-yi XIE
1
;
Sheng-hui SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Amiodarone; therapeutic use; Anti-Arrhythmia Agents; therapeutic use; Atrial Fibrillation; drug therapy; Biphenyl Compounds; therapeutic use; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Male; Middle Aged; Phytotherapy; Tetrazoles; therapeutic use
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26(7):644-646
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the curative effects of irbesartan, amiodarone and Wenxin Granule (WG), applied alone or in combination, on sinus rhythm maintenance in patients with auricular fibrillation (AF) after conversion.
METHODSForty-one patients of persistent AF, after their fibrillation being converted, were divided into three groups randomly, and treated with amiodarone (group A, n=14), irbesartan and amiodarone (group B, n=15), and WG plus irbesartan and amiodarone (group C, n=12) respectively for 6 months.
RESULTSCompared with that before treatment, the inner diameter of atria sinistrum reduced in group B and C, and the reduction in the latter was superior to that in the former (P < 0.05); the diameter of left ventricle also reduced in group C (P < 0.05); and the maintenance rate of sinus rhythm was higher in group C than that in group A (P < 0.05).
CONCLUSIONCombined therapy of Chinese and Western medicines shows synergistic effect of anti-arrhythmia.
