Research on Chinese medicine pairs effects of Panax notoginseng and Bletilla striata before and after compatibility on contents of notoginsenosides.
- Author:
Wen-Jun LIU
1
;
Ning-Bo CHENG
1
;
Zhao-Qing MENG
1
;
Hong-Qiang FEI
1
;
Lin SUN
1
;
Wen-Zhe HUANG
1
;
Zhen-Zhong WANG
1
;
Yue-Sheng WANG
1
;
Wei XIAO
1
Author Information
- Publication Type:Journal Article
- Keywords: (20S)-ginseng saponin Rg₃; Bletilla striata; Panax notoginseng; ginseng saponin Rh₄; lipase inhibitor
- From: China Journal of Chinese Materia Medica 2016;41(5):887-890
- CountryChina
- Language:Chinese
- Abstract: To discuss the synergistic mechanism of compatible use of two medicinal herbs,Panax notoginseng and Bletilla striata, an HPLC was established to determine two ginseng saponins (20S)-ginseng saponin Rg₃ and ginseng saponin Rh₄ contained in single decoction of Panax notoginseng as well as in compound decoction of Panax notoginseng and Bletillastriata in different compatibility ratio (1∶0.5, 1∶1, 1∶2), followed by analyzing the impact of amount of notoginsenosides after compatibility. As a result, compared with the single decoction of Panax notoginseng, the contents of ginseng saponin Rg₃ and ginseng saponin Rh₄ in the compound decoction of Panax notoginseng and Bletillastriata were on the rise as the increasement of the amount of Bletillastriata. The contents of the notoginsengsaponin R₁, ginseng saponin Rg₁ and ginseng saponin Rb₁ of Panax notoginseng single decoction were significantly decreased after compatibility. Therefore, after compatibility, it was more easy to produce (20S)-ginseng saponin Rg₃ and ginseng saponin Rh₄.This study can extend to a method of preparation of (20S)-ginseng saponin Rg₃ and ginseng saponin Rh₄. Furthermore, after compatibility, two ginseng saponins which had lipase inhibitory effect were both increased significantly, indicating that the compatibility of these two herb medicines may have effect on losing weight.
