A Case of Toxic Epiderma Nocrolysis.
- Author:
Soo Man CHAE
;
Jin Kue KIM
;
Jang Kue PARK
- Publication Type:Original Article
- MeSH:
Administration, Oral;
Adolescent;
Adult;
Burns;
Child;
Common Cold;
Epidermis;
Erythema;
Humans;
Male;
Sensation;
Skin
- From:Korean Journal of Dermatology
1979;17(6):469-473
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Toxic epidermal necrolysis(T.E.N.) is a toxic erythema of the skin that undergoes epidermal necrolysis and peding so that it appears to have been scalded. There seem to be two basic form of T.E.N. In children, the deavage of the epidermis that results from an acantholytic-dyskeratotic cytolytic process is in the malpighian or granular layer and is usually induced by a staphylococci toxin. In adult, it is characterized by a full-thicknees cytolytic cleavage of skin above the basal layer and is usually precipitated by a drug. The authors observed a 17 year-old male with T.E.N. He began to notify the erythematous skin lesion with burning sensation on the whole body surface at 12 hours after oral administration of some drugs for common cold and developed the characteristic flaccid bullous and denuded lesions with tenderness within next 20 hours.
