Therapeutic Application of Transcranial Magnetic Stimulation (TMS) in Depression.
- Author:
Jeong Ho CHAE
1
;
Chang Uk LEE
;
Won Myong BAHK
Author Information
1. Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Transcranial Magnetic Stimulation;
TMS;
Depression;
Antidepressant
- MeSH:
Brain;
Depression*;
Head;
Humans;
Magnetic Fields;
Neurons;
Transcranial Magnetic Stimulation*
- From:Korean Journal of Psychopharmacology
2003;14(2):77-83
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Transcranial magnetic stimulation (TMS) is a new, noninvasive procedure of a localized pulsed magnetic field to the surface of the head to cause a depolarization of neurons in the brain cortex underneath. Knowledge of the neuroanatomic abnormalities of depression is serving as the background for TMS treatment in depression. Here we provide a summarized review of the therapeutic application of TMS in patients with depression. METHODS: We described the clinical and basic researches of TMS in depression and integrated the future direction using literature review and interview with experts. RESULTS: The field of TMS is beginning to address the issues of using TMS as a novel antidepressant. The ability to excite local areas of brain cortex has raised the possibility of the use of TMS as a novel therapeutic tool for depression. CONCLUSIONS: Many parameters, such as intensity, location, frequency, pulse width, intertrain interval, coil type, duration, numbers of sessions, and interval between sessions remain to be systematically explored. However TMS would be a relatively new and noninvasive method to investigate regional brain activity and to treat depression.
