Gender Differences Among Korean Patients With Coronary Spasm.
10.4070/kcj.2009.39.10.423
- Author:
Ju Hwan LEE
1
;
Hyunsang LEE
;
Myung Hwan BAE
;
Yong Seop KWON
;
Jang Hoon LEE
;
Hyeon Min RYU
;
Yongwhi PARK
;
Dong Heon YANG
;
Hun Sik PARK
;
Yongkeun CHO
;
Shung Chull CHAE
;
Jae Eun JUN
;
Wee Hyun PARK
Author Information
1. Department of Internal Medicine, CHA University, CHA Gumi Medical Center, Gumi, Korea.
- Publication Type:Original Article
- Keywords:
Coronary vasospasm;
Sex differences
- MeSH:
Alcohol Drinking;
Chest Pain;
Constriction, Pathologic;
Coronary Angiography;
Coronary Vasospasm;
Ergonovine;
Female;
Humans;
Male;
Maleates;
Sex Characteristics;
Smoke;
Smoking;
Spasm;
Syncope
- From:Korean Circulation Journal
2009;39(10):423-427
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The gender differences among Korean patients with coronary spasm have not been defined. We thus determined the gender differences among Korean patients with coronary spasm. SUBJECTS AND METHODS: Patients with chest pain and/or syncope who were admitted to Kyungpook National University Hospital between January 2001 and August 2008 were included. Provocation of coronary vasospasm with intracoronary ergonovine maleate was performed when baseline coronary angiography showed no significant stenosis or there was a strong clinical suspicion of coronary spasm. The clinical characteristics were analyzed from 104 consecutive patients (56+/-9 years of age; 21 females) who were diagnosed with coronary spasm. RESULTS: Female patients were younger (52+/-7 vs. 57+/-10 years, p=0.046) with lower rates of smoking and alcohol consumption histories than male patients (19% vs. 65%, p<0.001; and 43% vs. 89%, p<0.001, respectively). The other clinical characteristics were not significantly different, except for the triglyceride levels. CONCLUSION: The majority of patients with coronary spasm were males who were smokers and alcohol consumers. The female patients had lower rates of smoking and alcohol consumption, and they were younger than the male patients. Further studies are needed to investigate the relevance of gender differences in the pathogenesis of coronary spasm.
