A case of Waldenstr's Macroglobulinemia with Pleural Involvement.
- Author:
Eun Ha LEE
1
;
Nam Hee RYU
;
Sang Gyung KIM
;
Chang Ho JEON
;
Hun Suk SUH
;
Dong Gun SHIN
Author Information
1. Department of Clinical Pathology, College of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Waldenstr's macroglobulinemia;
Plasmacytoid lymphocytes;
Pulmonary involvement
- MeSH:
Aged;
Bone Marrow;
Dyspnea;
Electrophoresis;
gamma-Globulins;
Humans;
Immunoglobulin M;
Lymphocytes;
Male;
Plasma Cells;
Waldenstrom Macroglobulinemia*
- From:Korean Journal of Clinical Pathology
1999;19(2):177-180
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Waldenstr's macroglobulinemia is a slowly progressing disease characterized by proliferation of small lymphocytes, plasmacytoid lymphocytes and plasma cells in the bone marrow with increased serum monoclonal IgM. Since 1944, only a few cases of Waldenstr's macroglobulinemia with pulmonary involvement have been described. We experienced a case of Waldenstr's macroglobulinemia with pulmonary involvement. The patient was 66-year-old male complaining dyspnea. His cytological finding of pleural fluid aspirates revealed many plasmacytoid lymphocytes. Serum electrophoresis showed the sharp M-peak in the gamma globulin region, which was identified as a IgM, kappa type by immunofixation. Bone marrow findings showed small lymphocytic and plasmacytoid lymphocytic infiltration.
