The Association of Plasma HDL-Cholesterol Level with Cardiovascular Disease Related Factors in Korean Type 2 Diabetic Patients.
10.4093/kdj.2008.32.3.215
- Author:
Hye Sook HONG
1
;
Jong Suk PARK
;
Han Kyoung RYU
;
Wha Young KIM
Author Information
1. Department of Food and Nutrition, Ewha Womans University, Korea.
- Publication Type:Original Article
- Keywords:
Cardiovascular disease;
Low HDL-cholesterolemia;
Nutrient intake;
Type 2 diabetes mellitus
- MeSH:
Adipose Tissue;
Cardiovascular Diseases;
Cause of Death;
Cholesterol;
Diabetes Mellitus, Type 2;
Diet;
Female;
Humans;
Lipoproteins;
Male;
Muscles;
Plasma;
Thiamine;
Vitamin E;
Vitamins
- From:Korean Diabetes Journal
2008;32(3):215-223
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Cardiovascular disease (CVD) is the major cause of death in type 2 diabetic patients. The purpose of this study was to investigate the characteristics of Korean type 2 diabetes mellitus (DM) patients according to plasma high density lipoprotein (HDL) cholesterol level and to document the effect of diet on HDL-cholesterol. METHODS: The subjects were 252 (male: 134, female: 118) Korean type 2 DM patients recruited from a general hospital's DM clinic and divided into low HDL-cholesterol group (male < 40 mg/dL, female < 50 mg/dL) and control group (male > or = 40 mg/dL, female > or = 50 mg/dL). Anthropometric and hematological variables and dietary intake were assessed by the groups. RESULTS: The subject's mean age was 60.2 +/- 1.1 years and duration of diabetes was 9.5 +/- 1.0 years. Anthropometric measurements (body fat mass, % body fat, WHR, fat free mass, and muscle mass) and BMI were not significantly different between two groups. The male subjects with low HDL-cholesterolemia showed higher Atherogenic Index (AI, P < 0.001) and higher % carbohydrate from energy than control group (P < 0.01). The female subjects with low HDL-cholesterolemia showed higher AI (P < 0.001) and a tendency of higher triglyceride level and lower intake of energy, protein, lipid, vitamin B1 and vitamin E (P < 0.05) than control group. CONCLUSION: The subject with low HDL-cholesterolemia showed significantly higher AI. Male subject with low HDL-cholesterolemia consumed higher carbohydrate and female subject with low HDL-cholesterolemia showed lower intakes of many nutrients. This result suggests the importance of an adequate and balanced diet to manage type 2 DM patients to prevent CVD complications.
