IgA Nephropathy Associated with Chronic Urate Nephropathy.
- Author:
Jin Hee CHO
1
;
Su Kyong YU
;
Jung Il PARK
;
Myoung Hee LEE
;
Nam Kyu LYMM
;
In Whee PARK
;
Heungsoo KIM
;
Hyunee YIM
;
Gyu tae SHIN
Author Information
1. Department of Nephrology, Ajou University school of Medicine, Suwon, Korea. gtshin@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
IgA nephropathy;
Uric acid;
Glomerulonephritis
- MeSH:
Biopsy;
Cell Proliferation;
Crystallins;
Edema;
Glomerulonephritis;
Glomerulonephritis, IGA;
Hematuria;
Immunoglobulin A;
Renal Insufficiency;
Uric Acid
- From:Korean Journal of Nephrology
2008;27(2):234-237
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
IgA nephropathy is the most common primary glomerulonephritis and characterized by deposition of IgA in glomerular mesangial area. Chronic urate nephropathy is characterized by precipitation of uric acid crystals in the collecting ducts and medullary interstitium. We report a case of IgA nephropathy associated with chronic urate nephropathy. A 57 year old man underwent percutaneous renal biopsy for gross hematuria, generalized edema and renal failure. Renal biopsy showed typical findings of IgA nephropathy: increased mesangial matrix, cellular proliferation and positive staining of IgA. In addition, crystalline deposits of uric acid, which is typical of chronic urate nephropathy, were seen in the medullary interstitium.