A Case of Hemolytic Transfusion Reaction Attributable to Anti-Jk(b) Abolished in the Enzyme Phase Reaction.
10.17945/kjbt.2016.27.1.79
- Author:
Sae Am SONG
1
;
Seung Hwan OH
;
Ja Young LEE
;
Sung Kyung SUNG
;
Jeong Hwan SHIN
;
Hye Ran KIM
;
Kyung Ran JUN
;
Jeong Nyeo LEE
Author Information
1. Department of Laboratory Medicine, Inje University College of Medicine, Busan, Korea. paracelsus@daum.net
- Publication Type:Case Report
- Keywords:
Kidd Blood-Group System;
Enzyme;
EDTA;
Hemolytic transfusion reaction
- MeSH:
Agglutination Tests;
Antibodies;
Blood Group Incompatibility*;
Blood Transfusion;
Edetic Acid;
Emergency Service, Hospital;
Erythrocytes;
Humans;
Kidd Blood-Group System;
Male;
Middle Aged;
Plasma
- From:Korean Journal of Blood Transfusion
2016;27(1):79-83
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of an intravascular hemolytic reaction attributable to anti-Jk(b) antibodies that were not detected using an enzyme phase antibody identification test. A 61-year-old male who had received two units of red blood cells was admitted to the emergency room because his urine was dark. LISS/Coombs gel column agglutination tests suggested the presence of anti-Jk(b) and anti-E antibodies. However, his serum was negative for the Jk(b) antigen when an enzyme phase test was performed. A positive reaction was evident, however, when EDTA-treated plasma was tested; this excluded any possible complement-mediated reaction. The patient was diagnosed with an intravascular hemolytic transfusion reaction, caused by anti-Jk(b), and was later discharged without specific complications after receiving antigen-negative blood transfusions.
