A Case of Self-healing Langerhans Cell Histiocytosis.
- Author:
Ki Baek JEONG
1
;
Hyun Chull KIM
;
Dong Hoon SHIN
;
Jong Soo CHOI
;
Ki Hong KIM
;
Dong Sug KIM
Author Information
1. Department of Dermatology, Yeungnam University College of Medicine, Daegu, Korea. dhshin@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Langerhans cell histiocytosis;
Self-healing
- MeSH:
Abdomen;
Edible Grain;
Coffee;
Dermis;
Eosinophils;
Erythrocytes;
Histiocytes;
Histiocytosis, Langerhans-Cell*;
Humans;
Infant;
Langerhans Cells;
Recurrence;
S100 Proteins;
Thorax;
Zea mays
- From:Korean Journal of Dermatology
2002;40(8):1007-1009
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Langerhans cell histiocytosis is a proliferative disease in which Langerhans cells accumulate in various body sites and cause damage to the affected organs. We report a 7-month-old infant who had only cutaneous lesions and healed spontaneously without treatment. There were rice grain to corn sized erythematous papules and crusted lesions in the chest, abdomen, and back for 2 months. The histologic finding of the lesion showed that the dyscohesive infiltrate, predominantly of histiocytes, were present and extravasated erythrocytes and eosinophils were also found in edematous papillary dermis. Careful examination showed histiocytes with coffee bean or kidney-shaped nucleus which was positive for S-100 protein. The infant had no systemic involvement, and healed spontaneously after 1 month without relapse.
