Evaluation of Aqueductal Patency in Patients with Hydrocephalus: Three-Dimensional High-Sampling-Efficiency Technique (SPACE) versus Two-Dimensional Turbo Spin Echo at 3 Tesla.
10.3348/kjr.2014.15.6.827
- Author:
Murat UCAR
1
;
Melike GURYILDIRIM
;
Nil TOKGOZ
;
Koray KILIC
;
Alp BORCEK
;
Yusuf ONER
;
Koray AKKAN
;
Turgut TALI
Author Information
1. Department of Radiology, School of Medicine, Gazi University, Ankara 06510, Turkey. drucar@yahoo.com
- Publication Type:Original Article ; Comparative Study
- Keywords:
Hydrocephalus;
Cerebrospinal fluid flow;
MRI;
3D-SPACE;
Aqueductal patency
- MeSH:
Adolescent;
Adult;
Aged;
Child;
Female;
Humans;
Hydrocephalus/*radiography;
Imaging, Three-Dimensional;
Magnetic Resonance Imaging;
Magnetic Resonance Imaging, Cine;
Male;
Middle Aged;
Retrospective Studies;
Sensitivity and Specificity;
Young Adult
- From:Korean Journal of Radiology
2014;15(6):827-835
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To compare the accuracy of diagnosing aqueductal patency and image quality between high spatial resolution three-dimensional (3D) high-sampling-efficiency technique (sampling perfection with application optimized contrast using different flip angle evolutions [SPACE]) and T2-weighted (T2W) two-dimensional (2D) turbo spin echo (TSE) at 3-T in patients with hydrocephalus. MATERIALS AND METHODS: This retrospective study included 99 patients diagnosed with hydrocephalus. T2W 3D-SPACE was added to the routine sequences which consisted of T2W 2D-TSE, 3D-constructive interference steady state (CISS), and cine phase-contrast MRI (PC-MRI). Two radiologists evaluated independently the patency of cerebral aqueduct and image quality on the T2W 2D-TSE and T2W 3D-SPACE. PC-MRI and 3D-CISS were used as the reference for aqueductal patency and image quality, respectively. Inter-observer agreement was calculated using kappa statistics. RESULTS: The evaluation of the aqueductal patency by T2W 3D-SPACE and T2W 2D-TSE were in agreement with PC-MRI in 100% (99/99; sensitivity, 100% [83/83]; specificity, 100% [16/16]) and 83.8% (83/99; sensitivity, 100% [67/83]; specificity, 100% [16/16]), respectively (p < 0.001). No significant difference in image quality between T2W 2D-TSE and T2W 3D-SPACE (p = 0.056) occurred. The kappa values for inter-observer agreement were 0.714 for T2W 2D-TSE and 0.899 for T2W 3D-SPACE. CONCLUSION: Three-dimensional-SPACE is superior to 2D-TSE for the evaluation of aqueductal patency in hydrocephalus. T2W 3D-SPACE may hold promise as a highly accurate alternative treatment to PC-MRI for the physiological and morphological evaluation of aqueductal patency.
