Detection of Hemorrhagic Transformation in Patients with Acute Cerebral Infarction: Comparison of CT with T1WI, FLAIR, and Gradient-Echo MR Imaging.
- Author:
Seok Kyun CHUNG
1
;
Jeong Jin SEO
;
Woong YOON
;
Yong Yeon JEONG
;
Tae Woong CHUNG
;
Gwang Woo JEONG
;
Heoung Keun KANG
Author Information
- Publication Type:Original Article
- Keywords: Brain, infarction; Hemorrhage, CT; Hemorrhage, MR
- MeSH: Cerebral Infarction*; Hemorrhage; Humans; Magnetic Resonance Imaging*; Prospective Studies
- From:Journal of the Korean Radiological Society 2003;49(1):1-6
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: To determine the diagnostic accuracy of T1-weighted, FLAIR, and GRE MR imagings in the detection of hemorrhagic transformation in patients with acute cerebral infarction and to compare it with CT. MATERAILS AND METHODS: Fifty-three patients with acute territorial cerebral infarction were studied prospectively. All patients underwent nonenhanced CT and MRI including the T1-weighted, FLAIR, and GRE. Lesion conspicuity of hemorrhage was scored as follows: 0-none; 1-suspicious; 2-sure. CT and MR imagings were reviewed two radiologists respectively. The mean value of the lesion conspicuity in each CT and MR sequences was compared by means of a Wilcoxon signed ranks test. The time intervals between CT and MR imagings ranged from 3 to 14 hours (mean; 7.6 hours). RESULTS: Hemorrhagic transformation was detected on nonenhanced CT in 26 of 53 patients. In the detection of hemorrhage in patients with acute cerebral infarction, T1-weighted and FLAIR MR imagings were inferior to NECT (p<0.05). By contrast, lesion conspicuity of GRE MR imaging was not different from that of CT (p=0.5). In addition, lesion conspicuity of GRE MR imaging was greater than that of CT in five patients on reader A and two patients on reader B. CONCLUSION: GRE MR imaging was superior to T1-weighted and FLAIR MR imagings, equal to nonenhanced CT in the detection of hemorrhagic transformation in patients with acute cerebral infarction.
