A Case of a Composite Adrenal Medullary Tumor of Pheochromocytoma and Ganglioneuroma Masquerading as Acute Pancreatitis.
10.3904/kjim.2006.21.2.141
- Author:
Eun Kyoung CHOI
1
;
Wan Ho KIM
;
Keun Yong PARK
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Konyang University, Daejeon, Korea. kypark@kyuh.co.kr
- Publication Type:Case Report
- Keywords:
Adrenal gland neoplasms;
Pheochromocytoma;
Ganglioneuroma;
Hyperamylasemia;
Pancreatitis
- MeSH:
Pheochromocytoma/*diagnosis;
Pancreatitis/*etiology;
Neoplasms, Multiple Primary/*diagnosis;
Middle Aged;
Male;
Humans;
Ganglioneuroma/*diagnosis;
*Adrenal Medulla;
Adrenal Gland Neoplasms/*diagnosis;
Acute Disease
- From:The Korean Journal of Internal Medicine
2006;21(2):141-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
Composite adrenal medullary tumors, composed of both pheochromocytoma and ganglioneuroma, are extremely rare, as are pheochromocytomas masquerading as acute relapsing pancreatitis. We recently experienced a case of a 48-year-old male with both these phenomena. The patient complained of an acute onset of intense abdominal discomfort. At the same time, pancreatic enzymes were increased in concentration. An abdominal computed tomographic scan revealed an enlarged pancreas and a 3-cm left adrenal incidentaloma. Biochemical and 131I-MIBG scintigraphic findings were compatible with a pheochromocytoma. Yet, he had no clinical manifestations suggesting pheochromocytoma. An adrenalectomy was performed and a composite adrenal medullary tumor of pheochromocytoma and ganglioneuroma was confirmed during a pathologic examination. This case illustrates two points: 1) acute abdominal intense discomfort and hyperamylasemia may be unusual presentations of pheochromocytomas; and 2) the possibility of the pheochromocytoma, albeit rare, should be considered when a relapsing pancreatitis of uncertain etiology develops.
