Epitheliotropic cutaneous lymphoma (mycosis fungoides) in a dog.
- Author:
Dong Ha BHANG
1
;
Ul Soo CHOI
;
Min Kyu KIM
;
Eun Hwa CHOI
;
Min Soo KANG
;
Cheol Yong HWANG
;
Dae Yong KIM
;
Hwa Young YOUN
;
Chang Woo LEE
Author Information
- Publication Type:Case Report
- Keywords: dog; epitheliotropic cutaneous lymphoma; hypercalcemia; mycosis fungoides; PTH-rP
- MeSH: Animals; Dog Diseases/drug therapy/*pathology; Dogs; Fatal Outcome; Isotretinoin/therapeutic use; Male; Mycosis Fungoides/drug therapy/pathology/*veterinary; Prednisolone/therapeutic use; Skin Neoplasms/drug therapy/pathology/*veterinary
- From:Journal of Veterinary Science 2006;7(1):97-99
- CountryRepublic of Korea
- Language:English
- Abstract: A seven-year-old castrated male Yorkshire terrier dog was presented for a recurrent skin disease. Erythematous skin during the first visit progressed from multiple plaques to patch lesions and exudative erosion in the oral mucosa membrane. Biopsy samples were taken from erythematous skin and were diagnosed with epitheliotropic T cell cutaneous lymphoma by histopathology and immunochemical stain. In serum chemistry, the dog had a hypercalcemia (15.7 mg/dl) and mild increased alkaline phosphatase (417 U/l). Immunohistochemistry was performed to detect parathyroid hormone-related peptide (PTH-rP) in epitheliotropic cutaneous lymphoma tissues but the neoplastic cells were not labeled with anti-PTH-rP antibodies. The patient was treated with prednisolone and isotretinoin. However, the dog died unexpectedly.
