Two Cases of Acute Renal Failure Associated with Non-fulminant Acute Hepatitis A.
- Author:
Sung Eun KIM
1
;
Soo Jin KIM
;
Hyoung Su KIM
;
Hee Sun KIM
;
Eun Sook NAM
;
Sang Kyu LEE
;
Su Rin SHIN
;
Hak Yang KIM
Author Information
1. Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. bacter@hallym.or.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Acute hepatits A;
Acute renal failure;
Acute tubular necrosis
- MeSH:
Acute Disease;
Adult;
Hepatitis A/complications/*diagnosis/pathology;
Humans;
Kidney Failure, Acute/complications/*diagnosis/pathology;
Male;
Renal Dialysis/methods
- From:The Korean Journal of Gastroenterology
2006;48(6):421-426
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hepatitis A is generally regarded as a mild, self-limiting disease of the liver. Acute renal failure has rarely been reported in association with non-fulminant acute hepatitis A. Acute tubular necrosis is the most common form of renal injury in such patients. We recently experienced two cases of hepatitis A in which acute renal failure occurred early in the course of the illness and had a clinical course suggestive of acute tubular necrosis. In both patients, the clinical course of renal dysfunction was almost parallel to that of hepatic dysfunction. Hemodialysis was performed in patient 1 because of severe uremia despite maintaining urine output more than 2,000 mL per day. On the other hand, hemodialysis was not performed in patient 2 who showed a rapid recovery of renal dysfunction. The renal biopsy of patient 1 demonstrated typical findings of acute tubular necrosis on microscopy.
