Biomimetic Polymer Scaffolds to Promote Stem Cell-Mediated Osteogenesis.
- Author:
Eunkyung KO
1
;
Seung Woo CHO
Author Information
1. Department of Biotechnology, Yonsei University, Seoul, Korea. Seungwoocho@yonsei.Ac.Kr
- Publication Type:In Vitro ; Review
- Keywords:
Bone tissue engineering;
Biomimetic scaffolds;
Stem cells;
Osteoinductivity
- MeSH:
Biomimetics*;
Bone and Bones;
Osteogenesis*;
Polymers*;
Stem Cells
- From:International Journal of Stem Cells
2013;6(2):87-91
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bone tissue engineering using stem cells with osteogenic potential is a promising avenue of research for bone defect reconstruction. Organic, inorganic, and composite scaffolds have all been engineered to provide biomimetic microenvironments for stem cells. These scaffolds are designed to promote stem cell osteogenesis. Here, we review current technologies for developing biomimetic, osteoinductive scaffolds for stem cell applications. We summarize the reported in vitro and in vivo osteogenic effects of these scaffolds on stem cells.