Detection of Liver Metastases: Usefulness of Dynamic Spiral CT during the Portal Phase with a Higher IV Injection Rate of Contrast Material.
10.3348/jkrs.1996.35.1.87
- Author:
Youn Sin JEONG
1
;
June Sik CHO
;
Wan Gyu YOUN
;
Young Jun AHN
;
Chang Lak CHOI
;
Young Hwan LEE
Author Information
1. Department of Diagnostic Radiology, Chungnam National University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Liver neoplasms, secondary;
Liver neoplasms, CT;
Computed tomography(CT), helical
- MeSH:
Humans;
Liver*;
Neoplasm Metastasis*;
Tomography, Spiral Computed*
- From:Journal of the Korean Radiological Society
1996;35(1):87-92
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the usefulness of dynamic spiral computed tomography(CT) during the portal phase with ahigher IV injection rate of contrast material in detecting hepatic metastases. MATERIALS AND METHODS: We reviewed two-phase dynamic spiral CT in 44 patients with hepatic metastases of pathologically proven primary malignancy. One hundred and fifty ml. of non-ionic contrast material was administered with a power injector at a rate of 5ml/sec., and two-phase images at 55-80 sec.(portal phase) and 2-5 min.(equilibrium phase) were obtained after thestart of bolus injection. Two phase images were compared for detectability of hepatic metastases according tosize, number and enhancement pattern. RESULTS: In cases of metastases less than 1cm, 113 lesions(100%) that showed clearly defined hypodense lesions were detected in the portal phase of dynamic CT. However, the equilibriumphase images showed hypodense lesions in 58 cases(51%) and isodense lesions in 55cases(49%). In cases of metastases 1-2cm in size, the portal phase images detected 70 hypodense lesions(92%) and six hyperdense lesions(8%). In the equilibrium phase, however, the lesions were hypodense in 54 cases(71%), hyperdense infour(5%), and isodense in 18(24%). In cases of metastases larger than 2 cm, portal phase images showed 29 hypodense lesions(97%) and one hyperdense lesion(3%). In the equilibrium phase, however, the lesions were hypodense in 25 cases(83%), hyperdense in two(7%), and mixed in three(10%). As compared with the portal phase, most metastatic lesions were detected as poorly defined hypodense or isodense lesions in the equilibrium phase and decrease in size due to peripheral enhancement. CONCLUSION: Dynamic spiral CT during the portal phase with a higher IV injection rate(5 ml/sec) of contrast material is a useful method for detecting hepatic metastases, especially small lesions less than 1cm.