Risk Factors Associated with Premalignant and Malignant Endometrial Polyps.
10.6118/jksm.2013.19.2.74
- Author:
Hee Suk LEE
1
;
Yeon Jean CHO
;
Joo Myung KIM
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Dong-A University, Busan, Korea.
- Publication Type:Original Article
- Keywords:
Endometrial neoplasm;
Hysteroscopy;
Menopause;
Metrorrhagia;
Polyps
- MeSH:
Endometrial Neoplasms;
Female;
Humans;
Hyperplasia;
Hysteroscopy;
Medical Records;
Menopause;
Metrorrhagia;
Odds Ratio;
Polyps;
Postmenopause;
Prevalence;
Risk Factors;
Uterine Hemorrhage
- From:The Journal of Korean Society of Menopause
2013;19(2):74-80
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: The objective of this study is to evaluate the prevalence of endometrial premalignant and malignant polyps in women who underwent hysteroscopic polypectomies, and to investigate whether clinical parameters predict histopathologic outcomes. METHODS: A review was carried out on the medical records of patients who had undergone hysteroscopic endometrial polypectomy from January 2010 to December 2011. One thousand one hundred ninety-six women who ranged in age from 16 to 81 years were included in the study. Polyps were classified as benign (endometrial polyps and polyps with non-atypical simple hyperplasia and non-atypical complex hyperplasia), premalignant (polyps with atypical simple hyperplasia or atypical complex hyperplasia), or malignant. A statistical analysis was then performed. RESULTS: Histopathologically, 96.7% benign, 1.1% premalignant, and 2.2% malignant lesions were detected. Abnormal uterine bleeding and postmenopause were the only factors which were determined to be associated with a higher risk of malignancy, with an odds ratios of 5.07 (95% CI, 2.25-11.41) and 3.41 (95% CI, 1.14-10.24), respectively. CONCLUSION: The risk factors associated with premalignant and malignant endometrial polyps include abnormal uterine bleeding and menopause.
