Association between Serum Homocysteine Concentrations and Bone Mineral Density in Middle Aged Women.
10.6118/jksm.2013.19.2.81
- Author:
Ari KIM
1
;
Jun Hee LEE
;
Ji Young LEE
;
Young Min OH
;
Sung Nam HONG
;
Hoon CHOI
;
Eun Ae JAE
;
Hae Hyeog LEE
;
Heung Yeol KIM
Author Information
1. Institute of Wonkwang Medical Science, College of Medicine, Wonkwang University, Iksan, Korea.
- Publication Type:Original Article
- Keywords:
Bone density;
Homocysteine;
Osteoporosis
- MeSH:
Body Mass Index;
Bone Density;
Female;
Femur Neck;
Homocysteine;
Humans;
Hyperhomocysteinemia;
Mass Screening;
Middle Aged;
Osteoporosis;
Postmenopause;
Premenopause;
Risk Assessment;
Spine
- From:The Journal of Korean Society of Menopause
2013;19(2):81-86
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Hyperhomocysteinemia is known to be related with the early onset of osteoporosis. This study was to examine the association between serem homocysteine levels and bone mineral density (BMD) in middle aged women. METHODS: The study included 409 women who underwent bone density tests in the health screening centers from January 2009 to october 2010. Serum homocysteine levels and BMD were measured. RESULTS: Postmenopause group (n = 109) showed significantly lower BMD score in lumbar spine and femoral neck and significantly higher serum homocysteine concentration compared to premenopause group (n = 300). However, after adjusting for age, body mass index, and the menopausal condition in total 409 women, there were no significant correlations between serum homocysteine levels and BMD. CONCLUSION: Measurement of serum homocysteine levels may not be useful, but adjunctive for the risk assessment of osteoporosis in middle aged women.
