Overlap Syndrome of Amyopathic Antisynthetase Syndrome and Systemic Lupus Erythematosus: A Case Report.
10.4078/jkra.2007.14.4.363
- Author:
Soon Young KO
1
;
Tae Ho SEO
;
Seung Min LEE
;
Yun Mi JANG
;
Hae Rim KIM
;
Sang Heon LEE
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. shlee@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Atnisynthetase syndrome;
Anti-Jo-1 antibody;
Interstitial lung diseases;
Systemic lupus erythematosus
- MeSH:
Antibodies;
Arthritis;
Autoantibodies;
Biomarkers;
Connective Tissue Diseases;
Dyspnea;
Early Diagnosis;
Female;
Humans;
Lung Diseases, Interstitial;
Lupus Erythematosus, Systemic*;
Middle Aged;
Muscle Weakness;
Myositis
- From:The Journal of the Korean Rheumatism Association
2007;14(4):363-368
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Interstitial lung disease (ILD) with autoantibodies against antisynthetase may occur in the absence of clinically apparent myositis. We report 58-year-old woman who initially presented with dyspnea. The patient showed positive immunologic markers reflecting systemic lupus erythematosus, destructive polyarthritis, Raynaud's phenomenon, and ILD. There is no proximal muscle weakness in her symptoms. This syndrome was confirmed by positive antibodies to Jo-1. For the early diagnosis of this syndrome, the possibility of this syndrome including other connective tissue disease should be considered in patients presenting with symptoms related to ILD and positive anti-nuclear antibody.
