A case of infective endocarditis with endophthalmitis and septic arthritis caused by pneumococcal bacteremia.
- Author:
Joo Hui KIM
1
;
Jung Min JO
;
Mi Seon SHIN
;
Min Jung KIM
;
You Jin CHANG
;
Hyun LIM
;
Chang Min CHOI
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea. ccm@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Streptococcus pneumoniae;
Endocarditis;
Endophthalmitis;
Infectious arthritis
- MeSH:
Aged;
Anti-Bacterial Agents;
Aortic Valve;
Arthritis, Infectious;
Bacteremia;
Blindness;
Endocarditis;
Endophthalmitis;
Fever;
Heart Murmurs;
Humans;
Male;
Penicillins;
Small Cell Lung Carcinoma;
Streptococcus pneumoniae;
Vitrectomy;
Wrist
- From:Korean Journal of Medicine
2010;78(4):499-502
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pneumococcal endocarditis accompanied by pneumococcal bacteremia is a rare condition. However, its clinical course is typically aggressive and associated with high morbidity and mortality rates. We report a case of a 67-year-old male who had small cell lung cancer and was undergoing concurrent chemoradiation therapy, and who presented with pneumococcal bacteremia complicated by infective endocarditis, endogenous endophthalmitis, and septic arthritis of the wrist. He presented with fever, sudden blindness, and a systolic cardiac murmur. Blood cultures were positive for penicillin susceptible Streptococcus pneumoniae. Despite appropriate treatment with intravenous and intravitreal antibiotics, destructive changes still appeared in his vitreous, mitral, and aortic valves. He underwent a vitrectomy and mitral and aortic valve replacement. We were able to prevent further embolic events with antibiotics and early surgical management.