Incidence and Risk Factors of Irritable Bowel Syndrome in Community Subjects with Culture-proven Bacterial Gastroenteritis.
- Author:
Seong Joon KOH
1
;
Dong Ho LEE
;
Sang Hyub LEE
;
Young Soo PARK
;
Jin Hyeok HWANG
;
Jin Wook KIM
;
Sook Hyang JEONG
;
Nayoung KIM
;
Jong Pil IM
;
Joo Sung KIM
;
Hyun Chae JUNG
Author Information
- Publication Type:Original Article
- Keywords: Irritable bowel syndrome; Bacterial gastroenteritis; Diarrhea
- MeSH: Adolescent; Adult; Aged; Cohort Studies; Diarrhea/complications; Dysentery/complications; Female; Follow-Up Studies; Gastroenteritis/*complications/epidemiology/microbiology; Humans; Incidence; Irritable Bowel Syndrome/*diagnosis/epidemiology/etiology; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Factors; Salmonella/isolation & purification; Shigella/isolation & purification; Young Adult
- From:The Korean Journal of Gastroenterology 2012;60(1):13-18
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: The aim of this study was to investigate the incidence and risk factors of irritable bowel syndrome (IBS) in community subjects with culture-proven bacterial gastroenteritis. METHODS: This was a prospective, community-based, cohort study, which followed patients with a recent history of culture-proven bacterial gastroenteritis. IBS was diagnosed with the use of the Rome II criteria at 3 and 6 months after bacterial dysentery. RESULTS: Sixty five cases were included and completed the 6 month follow-up. Thirty four cases (52.3%) were female. Salmonella was the pathogen most frequently identified and seen in 41 patients (63.1%). The cumulative incidence of IBS among patients with microbiologically proven bacterial gastroenteritis within a community was 9.2% and 12.3% at 3 and 6 months of follow-up, respectively. The duration of initial diarrhea (> or =7 days) was associated with an increased risk for the development of IBS (aOR, 14.50 [95% CI, 1.38-152.72]; p=0.022). CONCLUSIONS: Our study suggests that the incidence of IBS among patients with culture-proven bacterial gastroenteritis within a community is similar to that reported among Western populations. A large, prospective study is encouraged to confirm our results and to evaluate the influence of the microbial species on the epidemiology of IBS in Asian populations.
