A Case of Pulmonary Hemosiderosis that was Dissolved by an Oral Prednisolone and the Milk Avoidance.
10.7581/pard.2012.22.4.422
- Author:
Mi Suk KIM
1
;
Ju Kyung LEE
;
Jun Hyuk SONG
;
Young Yull KOH
;
Woo Sun KIM
;
Young Hun CHOI
;
Dong In SUH
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. dongings0@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Pulmonary hemosiderosis;
Milk allergy;
Heiner's syndrome;
Avoidance
- MeSH:
Anemia;
Anti-Bacterial Agents;
Antibodies;
Biopsy;
Bronchoalveolar Lavage;
Dyspnea;
Fever;
Hemosiderosis;
Immunoglobulin G;
Lung;
Lung Diseases;
Macrophages;
Methylprednisolone;
Milk;
Milk Hypersensitivity;
Pneumonia;
Prednisolone;
Sepsis
- From:Pediatric Allergy and Respiratory Disease
2012;22(4):422-427
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 29-month-old boy presented with fever, dyspnea, and paleness. He was initially diagnosed with pneumonia and severe sepsis. Although he was treated with intravenous antibiotics and high dose methylprednisolone, dyspnea and paleness recurred two times. Under suspicion of pulmonary hemosiderosis, we performed video-assisted thoracoscopic lung biopsy and bronchoalveolar lavage on him and found hemosiderin-laden macrophages in both specimens. Despite thorough history and laboratory examination, we could not find any pathologic or serologic evidence for primary and secondary causes of pulmonary hemosiderosis except for one that indicating Heiner's syndrome. After taking oral prednisolone he showed improvement of anemia and dyspnea, which was maintained by milk avoidance. Based on the history and the existence of immunoglobulin G antibodies against milk components, we are considering it as the case of Heiner's syndrome.
