A Case of Ankylosing Spondylitis with Follicular Lymphoma.
10.4078/jrd.2011.18.4.315
- Author:
Hee Jin PARK
1
;
Yoon Hea PARK
;
Kyeong Hye PARK
;
Mihyun KIM
;
Eun Yeong CHOE
;
Jung Woo HAN
;
Ji Young HONG
;
Myung Hee CHANG
;
Sun Jung KIM
;
Joo Eun SHIM
;
Jeong Hae KIE
;
Sang Won LEE
;
Yong Beom PARK
;
Soo Kon LEE
;
Chan Hee LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Ankylosing spondylitis;
Non-Hodgkin's lymphoma;
Follicular lymphoma;
Inflammatory back pain
- MeSH:
Adult;
Back Pain;
Buttocks;
Hematologic Neoplasms;
Hip;
HLA-B27 Antigen;
Hodgkin Disease;
Humans;
Inflammation;
Korea;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive;
Lymphoma;
Lymphoma, Follicular;
Lymphoma, Non-Hodgkin;
Male;
Multiple Myeloma;
Naproxen;
Neoplasm Metastasis;
Sacroiliac Joint;
Spondylitis, Ankylosing
- From:Journal of Rheumatic Diseases
2011;18(4):315-319
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated that it is not associated with an increase in risk of malignant lymphomas. Cases of AS accompanied by hematologic malignancies such as multiple myeloma, chronic myelogenous leukemia, and Hodgkin's disease have been reported. In Korea, AS with non-Hodgkin's lymphoma or follicular lymphoma has not been reported. We experienced a 38-year-old male who had been diagnosed with follicular lymphoma with bone metastasis, who achieved complete remission after having been treated with chemotherapy, developed new inflammatory back pain. An MRI of his hip showed an active inflammation of the left sacroiliac joint and a positive HLA-B27. The patient was diagnosed with AS and was treated with naproxen, which improved the pain in his back and buttock.