Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease.
- Author:
Dae Young HYUN
1
;
Myung Ho JEONG
;
Doo Sun SIM
;
Yun Ah JEONG
;
Kyung Hoon CHO
;
Min Chul KIM
;
Hyun Kuk KIM
;
Hae Chang JEONG
;
Keun Ho PARK
;
Young Joon HONG
;
Jun Han KIM
;
Youngkeun AHN
;
Jung Chaee KANG
Author Information
- Publication Type:Original Article
- Keywords: Coronary artery disease; Left main stem; Percutaneous coronary intervention
- MeSH: Acute Coronary Syndrome*; Angina Pectoris; Angina, Stable*; Coronary Artery Disease*; Coronary Vessels*; Follow-Up Studies; Hospital Mortality; Humans; Hypertension; Male; Mortality; Multivariate Analysis; Percutaneous Coronary Intervention*; Stents; Survival Rate; Ultrasonography
- From:The Korean Journal of Internal Medicine 2016;31(6):1084-1092
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: This study appraised the long term clinical outcomes of patients treated with percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease. There are limited data regarding long-term clinical outcomes after PCI for ULMCA disease. METHODS: From 2001 to 2011, a total of 448 patients who underwent PCI for ULMCA disease and had 2-year clinical follow-up, were analyzed. The study patients were divided into two groups: group I (stable angina pectoris [SAP], n = 60, 48 men, 62 ± 10 years) and group II (acute coronary syndrome [ACS], n = 388, 291 men, 64 ± 10 years). We evaluated clinical and angiographic characteristics and major adverse cardiac events (MACE) during 2-year clinical follow-up. RESULTS: Mean age of studied patients was 64 ± 10 years with 339 male patients. Average stent diameter was 3.6 ± 0.4 mm and stent length was 19.7 ± 6.3 mm. Stent implantation techniques and use of intravascular ultrasound guidance were not different between two groups. In-hospital mortality was 0% in group I and 7% in group II (p = 0.035). One-month mortality was 0% in group I and 7.7% in group II (p = 0.968). Two-year survival rate was 93% in the group I and 88.4% in the group II (p = 0.921). Predictive factors for 2-year MACE were hypertension, Killip class ≥ 3, and use of intra-aortic balloon pump by multivariate analysis. CONCLUSIONS: Although in-hospital mortality rate was higher in ACS than in SAP, clinical outcomes during 2-year clinical follow-up were similar between SAP and ACS after PCI of ULMCA.
