Undifferentiated Pleomorphic Sarcoma in Mandible.
- Author:
Chul Hwan KIM
1
;
Jong Won JANG
;
Moon Young KIM
;
Yong Hwan KIM
;
Hang Gul KIM
;
Joo Hwan KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University, Korea. kimchoms@dankook.ac.kr
- Publication Type:Case Report
- Keywords:
Undifferentiated pleomorphic sarcoma;
Malignant fibrous histiocytoma;
Mandible;
Immunohistochemical study
- MeSH:
Adult;
Chemotherapy, Adjuvant;
Diagnosis;
Electrons;
Fibroblasts;
Free Tissue Flaps;
Histiocytes;
Histiocytoma, Malignant Fibrous;
Humans;
Mandible*;
Sarcoma*
- From:Maxillofacial Plastic and Reconstructive Surgery
2014;36(6):303-307
- CountryRepublic of Korea
- Language:English
-
Abstract:
Undifferentiated pleomorphic sarcoma (UPS), previously known as malignant fibrous histiocytoma, occurs commonly in the soft tissues in adult, but is rare in the maxillofacial region. It consists of undifferentiated mesenchymal tumor cells resembling histiocytes and fibroblasts. The purpose of this article is to report a case of UPS in the mandible. A 44-year-old patient presented with a painful growing mass in the mandible of two months' duration. Computed tomography and positron emission tomography-computed tomography revealed an ill-defined heterogenous, hypermetabolic mass about 4 cm in size in the left mandible invading adjacent soft tissues. A left mandiblulectomy and reconstruction with a fibular free flap were performed. Immunohistochemical study gave a diagnosis of UPS. The patient was referred for adjuvant chemotherapy after surgical removal of the tumor.
