Topiramate can reduce the number of episodic attacks in cyclic vomiting syndrome:a case report.
10.3345/kjp.2007.50.4.386
- Author:
Mi Sun YUM
1
;
Keun Wook BAE
;
Su Jeong YOU
;
Tae Sung KO
Author Information
1. Department of Pediatrics, Asan Medical Center, College of Medicine, University of Ulsan, Korea. tsko@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Vomiting;
Topiramate;
Migraine;
Child
- MeSH:
Brain;
Child;
Child, Preschool;
Humans;
Magnetic Resonance Imaging;
Male;
Migraine Disorders;
Vomiting*
- From:Korean Journal of Pediatrics
2007;50(4):386-389
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cyclic vomiting syndrome (CVS) is a paroxysmal, recurrent vomiting disorder of unknown pathophysiology and target organ. It has been hypothesized that CVS shares the same mechanism as migraine. We describe here a 5-year-old boy with CVS characterized by episodic vomiting attacks. These recurrent vomiting episodes began at 3 years of age, occurred every month and lasted for 5 days at a time. At the time of admission, no abnormal physical or neurological findings were observed and laboratory findings, including brain MRI and endoscopic examination, revealed nothing specific. The vomiting episodes were self-limited but recurrent and severely interrupted his daily life. When this patient was treated with topiramate, he showed a marked increase of symptom-free periods.
