Mixed Adenoneuroendocrine Gastric Carcinoma: A Case Report and Review of the Literature.
- Author:
Giovanni Battista LEVI SANDRI
1
;
Fabio CARBONI
;
Mario VALLE
;
Paolo VISCA
;
Alfredo GAROFALO
Author Information
- Publication Type:Case Report
- Keywords: Stomach neoplasms; Mixed tumor; Collision tumor; Adenoneuroendocrine; Surgery
- MeSH: Adenocarcinoma; Aged; Anemia; Anorexia; Biopsy; Combined Modality Therapy; Diagnosis; Endoscopy, Digestive System; Female; Follow-Up Studies; Gastrectomy; Humans; Nausea; Recurrence; Stomach; Stomach Neoplasms; Ulcer; Weight Loss
- From:Journal of Gastric Cancer 2014;14(1):63-66
- CountryRepublic of Korea
- Language:English
- Abstract: We present a rare case of a gastric mixed adenoneuroendocrine tumor and review the related English literature. A 77-year-old Caucasian woman was admitted to our department with nausea, anorexia, weight loss, and anemia. Esophagogastroduodenoscopy showed a large (>7 cm) ulcerative mass in the greater curvature of the stomach. Biopsy showed the presence of an adenocarcinoma with moderate differentiation. The patient underwent D2 subtotal gastrectomy. Histopathological analysis revealed a diagnosis of mixed gastric adenoneuroendocrine carcinoma. The post-operative course was uneventful, and at the 6-month follow-up, the patient was alive without evidence of recurrence. Our review of the English literature suggested that such cases are most often reported from eastern countries. Multimodal treatment should be the aim for these patients because of the neuroendocrine component of the tumor.
