Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts.
10.11005/jbm.2014.21.3.163
- Author:
Kyoji IKEDA
1
;
Sunao TAKESHITA
Author Information
1. Department of Bone and Joint Disease, National Center for Geriatrics and Gerontology, Obu, Japan. kikeda@ncgg.go.jp
- Publication Type:Review
- Keywords:
Bone remodeling;
Bone resorption;
Osteoblasts;
Osteoclasts
- MeSH:
Adult;
Bone Diseases, Metabolic;
Bone Remodeling;
Bone Resorption*;
Humans;
Osteoblasts*;
Osteoclasts*;
Osteogenesis;
Osteoporosis;
Skeleton
- From:Journal of Bone Metabolism
2014;21(3):163-167
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone disease such as osteoporosis ensues. Among multiple phases of the complex remodeling process, we focus in this review on factors and mechanisms that are involved in the coupling of bone formation to preceding resorption.
