Unexpected Fatal Hypernatremia after Successful Cardiopulmonary Resuscitation with Therapeutic Hypothermia: A Case Report.
10.3346/jkms.2012.27.3.329
- Author:
Sang Sik CHOI
1
;
Won Young KIM
;
Won KIM
;
Kyung Su LIM
Author Information
1. Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. wonpia@yahoo.co.kr
- Publication Type:Case Reports
- Keywords:
Hypernatremia;
Diabetes Insipidus;
Hypoxia, Brain;
Hypothermia, Induced
- MeSH:
Adult;
Cardiopulmonary Resuscitation/*adverse effects;
Diabetes Insipidus, Neurogenic/diagnosis/etiology;
Fatal Outcome;
Female;
Heart Arrest/complications/therapy;
Humans;
Hypernatremia/*etiology;
Hypothermia, Induced/*adverse effects;
Pulmonary Embolism/complications
- From:Journal of Korean Medical Science
2012;27(3):329-331
- CountryRepublic of Korea
- Language:English
-
Abstract:
Central diabetes insipidus (DI), characterized by unexpected fatal hypernatremia, is a rare complication after successful cardiopulmonary resuscitation with therapeutic hypothermia, but may be potentially fatal if recognition is delayed. We describe here a patient who experienced cardiac arrest due to a pulmonary embolism, followed by successful resuscitation after induction of therapeutic hypothermia. The patient, however, suddenly developed unexpected hypernatremia with increased urine output and was diagnosed with central DI as a complication of cerebral edema, and eventually died. Our findings suggest that central DI should be considered as a possible complication following unexpected hypernatremia with increased urine output during therapeutic hypothermia and that desmopressin acetate should be used to treat central DI.
