Thicknesses of Macular Retinal Layer and Peripapillary Retinal Nerve Fiber Layer in Patients with Hyperopic Anisometropic Amblyopia.
- Author:
Sang Won YOON
1
;
Won Ho PARK
;
Seung Hee BAEK
;
Sang Mook KONG
Author Information
- Publication Type:Original Article
- Keywords: Hyperopic anisometropic amblyopia; Macular and retinal nerve fiber thickness; Optical coherence tomography
- MeSH: Amblyopia/complications/*pathology; Anisometropia/complications/*pathology; Child; Child, Preschool; Female; Humans; Macula Lutea/*pathology; Male; Nerve Fibers/*pathology; Optic Disk/*pathology; Prospective Studies; Retinal Ganglion Cells/*pathology; Tomography, Optical Coherence/methods
- From:Korean Journal of Ophthalmology 2005;19(1):62-67
- CountryRepublic of Korea
- Language:English
- Abstract: This prospective study was performed to measure the macular and the peripapillary retinal nerve fiber layer (RNFL) thicknesses using optical coherence tomography (OCT) in patients with anisometropic amblyopia. Thirty-one patients with hyperopic anisometropic amblyopia were included. The macular retinal thickness and the peripapillary RNFL thickness were measured using OCT. The mean refractive error was +3.71 diopters (D) and +1.00 D, the mean macular retinal thickness was 252.5 micrometer and 249.7 micrometer, and the mean RNFL thickness was 115.2 micrometer and 109.6 micrometer, in the amblyopic eye and the normal eye, respectively. OCT assessment of RNFL thickness revealed a significantly thicker RNFL in hyperopic anisometropic amblyopia (P=0.019), but no statistically significant difference was found in macular retinal thickness (P> 0.05). In conclusion, the amblyopic process may involve the peripapillary RNFL, but not the macula. However, further evaluation is needed.