Changes in Corneal Curvature and Histopathology following Scleral Cauterization in Rabbits.
- Author:
Jung Je PARK
1
;
Joo Hwa LEE
;
Jin Hyung YOO
Author Information
1. Department of Ophthalmology, Inje University, Sanggye Paik Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Corneal astigmatism;
Histopathologic change;
Scleral cauterization
- MeSH:
Astigmatism;
Cautery*;
Collagen;
Hemostasis;
Necrosis;
Rabbits*;
Sclera
- From:Journal of the Korean Ophthalmological Society
1995;36(11):1864-1869
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was carried out to evaluate the effect of cauterization on histopathology of sclera and corneal astigmatism. All rabbit eyes had corneal steepening in the vertical meridian after cauterization. The greatest astigmatism was noticed immediately after cauterized eyes and then was reduced gradually for a period of 2 months. Under light microscope, necrosis of collagen fibrils and inflammatory cells were found immediately after cauterization of the eyes. After 2 months, treated sclera was recovered to normal structure. Under electron microscope, tissue defect was found immediately after cauterization. At the 1st month, tissue defect was replaced by small collagen fibrils, however, these changes were much improved during a period of 2 months. This study suggest that gradual loss of corneal astigmatism following cauterization was correlated with the histopathologic healing process of cauterization. The author recommends usage of the lightest and briefest application of wet field bipolar cautery at the lowest power setting capable of achieving hemostasis for minimal astigmatism.