The Comparison of the Effect of Therapeutic Lrens, Collagen Shield, and Tarsorrhaphy on Stromal Inflammation after Photorefractive Keratectomy in a Rabbit model.
- Author:
In Sook KIM
1
;
Hyo Myung KIM
;
Hai Ryun JUNG
Author Information
1. Department of Ophthalmology, Korea University, College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Collagen shield;
Photorefractive keratectomy;
Tarsorrhaphy;
Therapeutic lens
- MeSH:
Adult;
Collagen*;
Cornea;
Corneal Stroma;
Humans;
Inflammation*;
Lasers, Excimer;
Pain, Postoperative;
Photorefractive Keratectomy*;
Rabbits
- From:Journal of the Korean Ophthalmological Society
1995;36(11):1870-1875
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reducing inflammation after photo refractive keratectomy may decrease postoperative pain and reduce corneal haze intensity. We evaluated the effect of the therapeutic lens(T-lens) and collagen shield on stromal inflammation. Adult New Zealand white rabbits were subjected to excimer laser PRK. Polymorphonuclear leukocytes(PMNs) of ablated corneal stroma were counted 10 hours after surgery with a microscope. The number of PMNs in the central cornea was lower in the T-lens group (29.77 +/- 11.6) and collagen shield group(36.77 +/- 5.9) than in the tarsorrhaphy group (75.33 +/- 14.6). Of all the groups, the eyes which were left unpatched showed the most marked infiltration of PMNs into the wound(226.83 +/- 18.2). The T-lens and collagen shield may reduce postoperative corneal haze intensity better than a pressure patch by suppression of stromal inflammation.
