A Case of Henoch-Schonlein Purpura with Hemorrhagic Bullae in a Child.
- Author:
Yeon Mi OH
1
;
Mi Rim JUNG
;
Hye Jeong CHOI
;
Hee Jeong CHA
;
Jin Young JEONG
Author Information
1. Department of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. jyjeong@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Henoch-Schonlein purpura;
Hemorrhagic bullae;
Leukocytoclastic vasculitis;
IgA;
Fibrinogen
- MeSH:
Abdominal Pain;
Adult;
Arthralgia;
Arthritis;
Biopsy;
Blister;
Buttocks;
Capillaries;
Child*;
Diagnosis;
Exanthema;
Fibrinogen;
Fluorescent Antibody Technique, Direct;
Humans;
Immunoglobulin A;
Lower Extremity;
Nephritis;
Purpura;
Purpura, Schoenlein-Henoch*;
Skin;
Vasculitis
- From:Journal of the Korean Society of Pediatric Nephrology
2006;10(1):40-44
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Henoch-Schonlein purpura(HSP) is a systemic small vessel vasculitis characterized by cutaneous purpura, arthritis, abdominal pain and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. In this case report, the patient presented with arthralgia and abdominal pain and had hemorrhagic bullae as a prominent manifestation of the disease. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis of dermal vessels and prominent IgA and fibrinogen deposits on capillary walls by direct immunofluorescence. We confirmed the diagnosis of HSP and observed improvement of clinical symptoms and signs within a few days after corticosteroid treatment. We therefore report a case with a review of the literature.
