A Case of Granular Cell Tumor.
- Author:
Ji Ho RYOU
1
;
Jae Young CHOI
;
Mu Hyoung LEE
Author Information
1. Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Granular cell tumor;
Neural origin
- MeSH:
Adult;
Desmin;
Granular Cell Tumor*;
Head;
Humans;
Male;
Microscopy;
Myoblasts;
Myoma;
Neck;
S100 Proteins;
Tongue;
Vimentin
- From:Korean Journal of Dermatology
1996;34(5):861-864
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granular cell tumors were originally described in 1926 by Abrikossoff as myoblastic myomas. They usually occur as solitary tumors but can be multiple in about 10% of cases. They have a predilection for the head, neck and tongue, but also occur in many other organs. Authors experienced a 37 year-old male patient with a granular cell tumor which exhibited the distinctive histopathologic appearance on light microscopy and electromicroscopy Also, granular cells were S-100 protein, vimentin and CD68 immunoreactive, but desmin and GFAP showed negative immunostaining. This finding suggests a neural origin for grenular cell tumors.
