A Case of Poststreptococcal Glomerulonephritis Representing Rapidly Progressive Glomerulonephritis in an Elderly Patient.
- Author:
Byoung Sun OH
1
;
Cheol Whee PARK
;
Se Na JANG
;
Hyun Jung JUNG
;
Kyoung Hee KIM
;
Hyun Wha CHUNG
;
Sang Woo HAN
;
Yoon Sik CHANG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. ysc543@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Poststreptococcal glomerulonephritis;
Rapidly progressive glomerulonephritis
- MeSH:
Aged*;
Biopsy;
Diagnosis;
Dyspnea;
Early Diagnosis;
Edema;
Glomerulonephritis*;
Humans;
Male;
Microscopy, Electron;
Nephrotic Syndrome;
Oliguria;
Proteinuria;
Rare Diseases;
Renal Dialysis
- From:Korean Journal of Nephrology
2006;25(6):1025-1028
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Postinfectious streptococcal glomerulonephritis (PSGN) presenting as a rapidly progressive glomerulonephritis (RPGN) and nephrotic syndrome (NS) is a rare disease in elderly patients. Here we report a case of PSGN with RPGN and NS in an elderly male patient with a complete recovery from his illness. A 73-year-old man was admitted for dyspnea, oliguria and generalized edema appearing after acute upper respiratory infection. On admission, he presented nephrotic range of proteinuria, decreased renal function with elevated ASO, and decreased C3 and CH50 concentrations. The renal biopsy showed marked cellular crescents in the glomeruli with collapsed glomerular tufts and inflammatory cell infiltration. There were prominent and various sizes of "humps" in subepithelial areas in electron microscopy. Under the diagnosis of PSGN with RPGN, we successfully treated the patient with steroid pulse therapy and hemodialysis. We would suggest that early diagnosis and aggressive steroid therapy should be indicated in the treatment of PSGN with RPGN.
