A case of multiple gastric carcinoid tumors associated with Sjogren's syndrome.
- Author:
Keun Jong CHO
1
;
Jin Soo KIM
;
Chang Whan KIM
;
Jae Kwang KIM
;
Sok Won HAN
;
In Sik CHUNG
;
Jean A KIM
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. kimchmd@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoid tumor;
Sjogren's syndrome
- MeSH:
Carcinoid Tumor*;
Enterochromaffin-like Cells;
Gastritis, Atrophic;
Prognosis;
Salivary Glands;
Sjogren's Syndrome*
- From:Korean Journal of Medicine
2006;71(5):551-557
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinoid tumors are rare endocrine neoplasms arising from the enterochromaffin or enterochromaffin-like cells. Gastric carcinoids associated with autoimmune atrophic gastritis and hypergastrinemia, are usually multiple and the prognosis are better compared to solotary lesions with out hypergastrinemia. Gastric carcinoids are commonly associated with other endocrine disorders or tumors, but any associations with autoimmune disorders other than autoimmune atrophic gastritis have rarely been reported. Sjogren's syndrome is an autoimmune exocrinopathy that primarily affects the salivary glands, but it can also involve almost any other part of the gut. The most common form of gastrointestinal involvement in Sjogren's syndrome is chronic atrophic gastritis, which can lead to hypergastrinemia and the subsequent development of carcinoid. However, gastric carcinoid tumor associated with Sjogren's syndrome has not yet been reported on. To the best of our knowledge, this is the first such case in the world. We report on this case along with review of the related literature.
