The Value of SPECT/CT in Localizing Pain Site and Prediction of Treatment Response in Patients with Chronic Low Back Pain.
10.3346/jkms.2014.29.12.1711
- Author:
Inki LEE
1
;
Hendra BUDIAWAN
;
Jee Youn MOON
;
Gi Jeong CHEON
;
Yong Chul KIM
;
Jin Chul PAENG
;
Keon Wook KANG
;
June Key CHUNG
;
Dong Soo LEE
Author Information
1. Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea. larrycheon@gmail.com
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Low Back Pain;
Tomography, Emission-Computed, Single-Photon;
Tomography, X-Ray Computed;
Pain Management;
Technetium-99m (Tc-99m), Methylene Diphosphonate (MDP)
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Chronic Pain/*diagnosis/*therapy;
Female;
Humans;
Low Back Pain/*diagnosis/*therapy;
Lumbar Vertebrae/radiography/radionuclide imaging;
Male;
Middle Aged;
Multimodal Imaging/methods;
Pain Measurement/*methods;
Reproducibility of Results;
Retrospective Studies;
Sensitivity and Specificity;
Tomography, Emission-Computed, Single-Photon/*methods;
Tomography, X-Ray Computed/*methods;
Treatment Outcome;
Young Adult
- From:Journal of Korean Medical Science
2014;29(12):1711-1716
- CountryRepublic of Korea
- Language:English
-
Abstract:
In many circumstances, causing sites of low back pain (LBP) cannot be determined only by anatomical imaging. Combined functional and morphological imaging such as bone scan with single-photon emission computed tomography/computed tomography (SPECT/CT) may be helpful in identifying active lesions. The purpose of this study was to evaluate the usefulness of bone SPECT/CT in localizing the pain site and the treatment of chronic LBP. One hundred seventy-five patients suffering from chronic LBP who underwent SPECT/CT were included, retrospectively. All of the patients received multiple general treatments according to the symptoms, and some of them underwent additional target-specific treatment based on SPECT/CT. Numerical rating scale (NRS) pain score was used to assess the pain intensity. Of 175 patients, 127 showed good response to the given therapies, while the rest did not. Overall, 79.4% of patients with definite active lesions showed good response. Patients with mild active or no lesions on SPECT/CT had relatively lower response rate of 63.0%. Good response was observed by the treatment with the guidance of active lesions identified on SPECT/CT. SPECT/CT could be useful in identifying active lesions in patients with chronic LBP and guiding the clinicians to use adequate treatment.
